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Non-natural olefin cyclopropanation catalyzed by diverse cytochrome P450s and other hemoproteins
Recent work has shown that engineered variants of cytochrome P450(BM3) (CYP102A1) efficiently catalyze non-natural reactions, including carbene- and nitrene-transfer reactions. Given the broad substrate range of natural P450 enzymes, we set out to explore if this diversity could be leveraged to gene...
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| Pubblicato in: | Chembiochem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287214/ https://ncbi.nlm.nih.gov/pubmed/25294253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402286 |
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