Paternal heterochromatin formation in human embryos is H3K9/HP1 directed and primed by sperm-derived histone modifications

The different configurations of maternal and paternal chromatin, acquired during oogenesis and spermatogenesis, have to be rearranged after fertilization to form a functional embryonic genome. In the paternal genome, nucleosomal chromatin domains are re-established after the protamine-to-histone exc...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: van de Werken, Christine, van der Heijden, Godfried W., Eleveld, Cindy, Teeuwssen, Miriam, Albert, Mareike, Baarends, Willy M., Laven, Joop S. E., Peters, Antoine H. F. M., Baart, Esther B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284653/
https://ncbi.nlm.nih.gov/pubmed/25519718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6868
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