Astaxanthin Activates Nuclear Factor Erythroid-Related Factor 2 and the Antioxidant Responsive Element (Nrf2-ARE) Pathway in the Brain after Subarachnoid Hemorrhage in Rats and Attenuates Early Brain Injury

Astaxanthin (ATX) has been proven to ameliorate early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH) by modulating cerebral oxidative stress. This study was performed to assess the effect of ATX on the Nrf2-ARE pathway and to explore the underlying molecular mechanisms of antiox...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Wu, Qi, Zhang, Xiang-Sheng, Wang, Han-Dong, Zhang, Xin, Yu, Qing, Li, Wei, Zhou, Meng-Liang, Wang, Xiao-Liang
Format: Artigo
Language:Inglês
Published: MDPI 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278222/
https://ncbi.nlm.nih.gov/pubmed/25528957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12126125
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