Multiple Drugs Compete for Transport via the Plasmodium falciparum Chloroquine Resistance Transporter at Distinct but Interdependent Sites

Mutations in the “chloroquine resistance transporter” (PfCRT) are a major determinant of drug resistance in the malaria parasite Plasmodium falciparum. We have previously shown that mutant PfCRT transports the antimalarial drug chloroquine away from its target, whereas the wild-type form of PfCRT do...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bellanca, Sebastiano, Summers, Robert L., Meyrath, Max, Dave, Anurag, Nash, Megan N., Dittmer, Martin, Sanchez, Cecilia P., Stein, Wilfred D., Martin, Rowena E., Lanzer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276893/
https://ncbi.nlm.nih.gov/pubmed/25378409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614206
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados