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Control of membrane gaps by synaptotagmin-Ca(2+) measured with a novel membrane distance ruler
Fast synchronous neurotransmitter release is triggered by calcium that activates synaptotagmin-1 (syt-1), resulting in fusion of synaptic vesicles with the presynaptic membrane. Syt-1 possesses two Ca(2+)-binding C2 domains that tether membranes via interactions with anionic phospholipids. It is cap...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Pub. Group
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4275583/ https://ncbi.nlm.nih.gov/pubmed/25500905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6859 |
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