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An internal ribosome entry site in the 5′ untranslated region of epidermal growth factor receptor allows hypoxic expression
The expression of epidermal growth factor receptor (EGFR/ERBB1/HER1) is implicated in the progress of numerous cancers, a feature that has been exploited in the development of EGFR antibodies and EGFR tyrosine kinase inhibitors as anti-cancer drugs. However, EGFR also has important normal cellular f...
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發表在: | Oncogenesis |
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Main Authors: | , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Nature Publishing Group
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4275558/ https://ncbi.nlm.nih.gov/pubmed/25622307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2014.43 |
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