An internal ribosome entry site in the 5′ untranslated region of epidermal growth factor receptor allows hypoxic expression

The expression of epidermal growth factor receptor (EGFR/ERBB1/HER1) is implicated in the progress of numerous cancers, a feature that has been exploited in the development of EGFR antibodies and EGFR tyrosine kinase inhibitors as anti-cancer drugs. However, EGFR also has important normal cellular f...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Oncogenesis
Huvudupphovsmän: Webb, T E, Hughes, A, Smalley, D S, Spriggs, K A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Short Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275558/
https://ncbi.nlm.nih.gov/pubmed/25622307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2014.43
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk