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An internal ribosome entry site in the 5′ untranslated region of epidermal growth factor receptor allows hypoxic expression
The expression of epidermal growth factor receptor (EGFR/ERBB1/HER1) is implicated in the progress of numerous cancers, a feature that has been exploited in the development of EGFR antibodies and EGFR tyrosine kinase inhibitors as anti-cancer drugs. However, EGFR also has important normal cellular f...
Shranjeno v:
| izdano v: | Oncogenesis |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4275558/ https://ncbi.nlm.nih.gov/pubmed/25622307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2014.43 |
| Oznake: |
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