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Copper-promoted hydration and annulation of 2-fluorophenylacetylene derivatives: from alkynes to benzo[b]furans and benzo[b]thiophenes

An efficient copper-promoted hydration reaction and its application in the synthesis of benzo[b]furan and benzo[b]thiophene derivatives is presented starting from readily available 2-fluorophenylacetylene derivatives. The key annulation step involves the hydration of the C–F bond of 2-fluorophenylac...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Li, Yibiao, Cheng, Liang, Liu, Xiaohang, Li, Bin, Sun, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273265/
https://ncbi.nlm.nih.gov/pubmed/25550754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.305
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