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Micropatterned comet assay enables high throughput and sensitive DNA damage quantification

The single cell gel electrophoresis assay, also known as the comet assay, is a versatile method for measuring many classes of DNA damage, including base damage, abasic sites, single strand breaks and double strand breaks. However, limited throughput and difficulties with reproducibility have limited...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mutagenesis
Hauptverfasser: Ge, Jing, Chow, Danielle N., Fessler, Jessica L., Weingeist, David M., Wood, David K., Engelward, Bevin P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272061/
https://ncbi.nlm.nih.gov/pubmed/25527723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/geu063
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