TAK1-ECSIT-TRAF6 Complex Plays a Key Role in the TLR4 Signal to Activate NF-κB

ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) is known as a multifunctional regulator in different signals, including Toll-like receptors (TLRs), TGF-β, and BMP. Here, we report a new regulatory role of ECSIT in TLR4-mediated signal. By LPS stimulation, ECSIT formed a high...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wi, Sae Mi, Moon, Gyuyoung, Kim, Juhong, Kim, Seong-Tae, Shim, Jae-Hyuck, Chun, Eunyoung, Lee, Ki-Young
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271209/
https://ncbi.nlm.nih.gov/pubmed/25371197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597187
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