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Visual Detection of Bacterial Pathogens via PNA-Based Padlock Probe Assembly and Isothermal Amplification of DNAzymes

[Image: see text] We have developed a self-reporting isothermal system for visual bacterial pathogen detection with single base resolution. The new DNA diagnostic is based on combination of peptide nucleic acid (PNA) technology, rolling circle amplification (RCA) and DNAzymes. PNAs are used as excee...

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Vydáno v:Anal Chem
Hlavní autoři: Gomez, Anastasia, Miller, Nancy S., Smolina, Irina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270401/
https://ncbi.nlm.nih.gov/pubmed/25415469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac5018748
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