Blood-Brain Barrier Permeable Gold Nanoparticles: An Efficient Delivery Platform for Enhanced Malignant Glioma Therapy and Imaging

The blood-brain barrier (BBB) remains a formidable obstacle in medicine, preventing efficient penetration of chemotherapeutic and diagnostic agents to malignant gliomas. Here, we demonstrate that a transactivator of transcription (TAT) peptide-modified gold nanoparticle platform (TAT-Au NP) with a 5...

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Pubblicato in:Small
Autori principali: Cheng, Yu, Dai, Qing, Morshed, Ramin, Fan, Xiaobing, Wegscheid, Michelle L., Wainwright, Derek A., Han, Yu, Zhang, Lingjiao, Auffinger, Brenda, Tobias, Alex L., Rincón, Esther, Thaci, Bart, Ahmed, Atique U., Warnke, Peter, He, Chuan, Lesniak, Maciej S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268041/
https://ncbi.nlm.nih.gov/pubmed/25104165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201400654
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