Mahanine, a novel mitochondrial complex-III inhibitor induces G0/G1 arrest through redox alteration-mediated DNA damage response and regresses glioblastoma multiforme

The Electron transport chain (ETC) is responsible for oxidative phosphorylation-mediated mitochondrial respiration. Here we wanted to address the mahanine-induced targeted pathways in glioblastoma multiforme (GBM) in the context of G0/G1 phase arrest and redox alteration. We have demonstrated mahani...

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Publicat a:Am J Cancer Res
Autors principals: Bhattacharya, Kaushik, Bag, Arup K, Tripathi, Rakshamani, Samanta, Suman K, Pal, Bikas C, Shaha, Chandrima, Mandal, Chitra
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266700/
https://ncbi.nlm.nih.gov/pubmed/25520856
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