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Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3(+) Treg cells
Adoptive transfer of antigen-specific, in vitro-induced Foxp3(+) Treg (iTreg) cells protects against autoimmune disease. To generate antigen-specific iTreg cells at high purity, however, remains a challenge. Whereas polyclonal T cell stimulation with anti-CD3 and anti-CD28 antibody yields Foxp3(+) i...
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| Published in: | J Immunol Methods |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4265731/ https://ncbi.nlm.nih.gov/pubmed/25108241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.07.012 |
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