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Bias and variance reduction in estimating the proportion of true-null hypotheses

When testing a large number of hypotheses, estimating the proportion of true nulls, denoted by [Formula: see text] , becomes increasingly important. This quantity has many applications in practice. For instance, a reliable estimate of [Formula: see text] can eliminate the conservative bias of the Be...

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Detalhes bibliográficos
Publicado no:Biostatistics
Main Authors: Cheng, Yebin, Gao, Dexiang, Tong, Tiejun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263223/
https://ncbi.nlm.nih.gov/pubmed/24963010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxu029
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