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Axonal Charcot-Marie-Tooth Disease Patient-Derived Motor Neurons Demonstrate Disease-Specific Phenotypes including Abnormal Electrophysiological Properties

OBJECTIVE: Charcot-Marie-Tooth Disease (CMT) is a group of inherited peripheral neuropathies associated with mutations or copy number variations in over 70 genes encoding proteins with fundamental roles in the development and function of Schwann cells and peripheral axons. Here, we used iPSC-derived...

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Bibliografske podrobnosti
izdano v:Exp Neurol
Main Authors: Saporta, Mario A., Dang, Vu, Volfson, Dmitri, Zou, Bende, Xie, Xinmin (Simon), Adebola, Adijat, Liem, Ronald K., Shy, Michael, Dimos, John T.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262589/
https://ncbi.nlm.nih.gov/pubmed/25448007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.10.005
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