Axonal Charcot-Marie-Tooth Disease Patient-Derived Motor Neurons Demonstrate Disease-Specific Phenotypes including Abnormal Electrophysiological Properties

OBJECTIVE: Charcot-Marie-Tooth Disease (CMT) is a group of inherited peripheral neuropathies associated with mutations or copy number variations in over 70 genes encoding proteins with fundamental roles in the development and function of Schwann cells and peripheral axons. Here, we used iPSC-derived...

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Enregistré dans:
Détails bibliographiques
Publié dans:Exp Neurol
Auteurs principaux: Saporta, Mario A., Dang, Vu, Volfson, Dmitri, Zou, Bende, Xie, Xinmin (Simon), Adebola, Adijat, Liem, Ronald K., Shy, Michael, Dimos, John T.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262589/
https://ncbi.nlm.nih.gov/pubmed/25448007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.10.005
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