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Bosutinib plus capecitabine for selected advanced solid tumours: results of a phase 1 dose-escalation study
BACKGROUND: This phase 1 study evaluated the maximum tolerated dose (MTD), safety, and efficacy of bosutinib (competitive Src/Abl tyrosine kinase inhibitor) plus capecitabine. METHODS: Patients with locally advanced/metastatic breast, pancreatic, or colorectal cancers; cholangiocarcinoma; or gliobla...
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| Publicado no: | Br J Cancer |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260032/ https://ncbi.nlm.nih.gov/pubmed/25290090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.508 |
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