Altered Transcriptional Control Networks with Trans-Differentiation of Isogenic Mutant-KRas NSCLC Models

Background: The capacity of cancer cells to undergo epithelial mesenchymal trans-differentiation has been implicated as a factor driving metastasis, through the acquisition of enhanced migratory/invasive cell programs and the engagement of anti-apoptotic mechanisms promoting drug and radiation resis...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Haley, John A., Haughney, Elizabeth, Ullman, Erica, Bean, James, Haley, John D., Fink, Marc Y.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259114/
https://ncbi.nlm.nih.gov/pubmed/25538889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00344
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