Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1

BACKGROUND: Endometrial cancer (EC) is the 8(th) leading cause of cancer death amongst American women. Most ECs are endometrioid, serous, or clear cell carcinomas, or an admixture of histologies. Serous and clear ECs are clinically aggressive tumors for which alternative therapeutic approaches are n...

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Vydáno v:BMC Cancer
Hlavní autoři: Rudd, Meghan L, Mohamed, Hassan, Price, Jessica C, O’Hara, Andrea J, Le Gallo, Matthieu, Urick, Mary Ellen, Cruz, Pedro, Zhang, Suiyuan, Hansen, Nancy F, Godwin, Andrew K, Sgroi, Dennis C, Wolfsberg, Tyra G, Mullikin, James C, Merino, Maria J, Bell, Daphne W
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258955/
https://ncbi.nlm.nih.gov/pubmed/25427824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-884
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