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Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance
BACKGROUND: Routine chemotherapy often cannot achieve good therapeutic effects because of multidrug resistance (MDR). MDR is frequently caused by the elevated expression of the MDR1 gene encoding P-glycoprotein (P-gp). E2F1 is a frequently overexpressed protein in human tumor cells that increases th...
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| Published in: | BMC Cancer |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258940/ https://ncbi.nlm.nih.gov/pubmed/25466554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-904 |
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