Dynamic range of GSK3α not GSK3β is essential for bidirectional synaptic plasticity at hippocampal CA3-CA1 synapses

Glycogen synthase kinase-3 (GSK3), particularly the isoform GSK3β, has been implicated in a wide range of physiological systems and neurological disorders including Alzheimer's Disease. However, the functional importance of GSK3α has been largely untested. The multifunctionality of GSK3 limits...

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Publicado en:Hippocampus
Autores principales: Shahab, Lion, Plattner, Florian, Irvine, Elaine E, Cummings, Damian M, Edwards, Frances A
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
Materias:
Rapid Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258099/
https://ncbi.nlm.nih.gov/pubmed/25208523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22362
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