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Kinetics of cardiac myosin isoforms in mouse myocardium are affected differently by presence of myosin binding protein-C

We tested whether cardiac myosin binding protein-C (cMyBP-C) affects myosin cross-bridge kinetics in the two cardiac myosin heavy chain (MyHC) isoforms. Mice lacking cMyBP-C (t/t) and transgenic controls (WT(t/t)) were fed L-thyroxine (T4) to induce 90/10% expression of α/β-MyHC. Non-transgenic (NTG...

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Bibliografiske detaljer
Udgivet i:J Muscle Res Cell Motil
Main Authors: Tanner, Bertrand C.W., Wang, Yuan, Robbins, Jeffrey, Palmer, Bradley M.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257873/
https://ncbi.nlm.nih.gov/pubmed/25287107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-014-9390-0
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