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Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity
AIMS: Erythromycin is a macrolide antibiotic, which is frequently used as a topical formulation for the treatment of acne. It is also known as an inhibitor of the cytochrome P450 (CYP) isoenzyme 3A4. In this study, the systemic availability of topical erythromycin, hence the influence on the activit...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4256632/ https://ncbi.nlm.nih.gov/pubmed/25139487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12497 |
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