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Rapamycin Ameliorates Nephropathy despite Elevating Hyperglycemia in a Polygenic Mouse Model of Type 2 Diabetes, NONcNZO10/LtJ

While rapamycin treatment has been reported to have a putatively negative effect on glucose homeostasis in mammals, it has not been tested in polygenic models of type 2 diabetes. One such mouse model, NONcNZO10/LtJ, was treated chronically with rapamycin (14 ppm encapsulated in diet) and monitored f...

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書誌詳細
出版年:PLoS One
主要な著者: Reifsnyder, Peter C., Doty, Rosalinda, Harrison, David E.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256216/
https://ncbi.nlm.nih.gov/pubmed/25473963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114324
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