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Rapamycin Ameliorates Nephropathy despite Elevating Hyperglycemia in a Polygenic Mouse Model of Type 2 Diabetes, NONcNZO10/LtJ

While rapamycin treatment has been reported to have a putatively negative effect on glucose homeostasis in mammals, it has not been tested in polygenic models of type 2 diabetes. One such mouse model, NONcNZO10/LtJ, was treated chronically with rapamycin (14 ppm encapsulated in diet) and monitored f...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Reifsnyder, Peter C., Doty, Rosalinda, Harrison, David E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256216/
https://ncbi.nlm.nih.gov/pubmed/25473963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114324
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