Gene Pathways That Delay Caenorhabditis elegans Reproductive Senescence

Reproductive senescence is a hallmark of aging. The molecular mechanisms regulating reproductive senescence and its association with the aging of somatic cells remain poorly understood. From a full genome RNA interference (RNAi) screen, we identified 32 Caenorhabditis elegans gene inactivations that...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Wang, Meng C., Oakley, Holly D., Carr, Christopher E., Sowa, Jessica N., Ruvkun, Gary
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256158/
https://ncbi.nlm.nih.gov/pubmed/25474471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004752
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