APOE4 influences β-amyloid burden in primary progressive aphasia and speech apraxia

BACKGROUND: Apolipoprotein E epsilon 4 (APOE4) is a risk factor for β-amyloid deposition in Alzheimer’s dementia. Its influence on β-amyloid deposition in speech and language disorders, including primary progressive aphasia (PPA), is unclear. METHODS: One hundred and thirty subjects with PPA or spee...

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Bibliographic Details
Published in:Alzheimers Dement
Main Authors: Josephs, Keith A., Duffy, Joseph R., Strand, Edythe A., Machulda, Mary M., Senjem, Matthew L., Lowe, Val J., Jack, Clifford R., Whitwell, Jennifer L.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254054/
https://ncbi.nlm.nih.gov/pubmed/24985533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2014.03.004
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