Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy

BACKGROUND: Mozambique implemented artemisinin-based combinations therapy (ACT) using artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in 2009. AL remains highly efficacious, but widespread use may soon facilitate emergence of artemisinin tolerance/resistance. The p...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Lobo, Elsa, de Sousa, Bruno, Rosa, Soraia, Figueiredo, Paula, Lobo, Lis, Pateira, Sara, Fernandes, Natercia, Nogueira, Fatima
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248432/
https://ncbi.nlm.nih.gov/pubmed/25098280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-300
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