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Cooperativity among secretory IgA, the polymeric immunoglobulin receptor, and the gut microbiota promotes host-microbial mutualism
Secretory IgA (SIgA) antibodies in the intestinal tract form the first line of antigen-specific immune defense, preventing access of pathogens as well as commensal microbes to the body proper. SIgA is transported into external secretions by the polymeric immunoglobulin receptor (pIgR). Evidence is r...
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Published in: | Immunol Lett |
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Main Author: | |
Format: | Artigo |
Language: | Inglês |
Published: |
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246051/ https://ncbi.nlm.nih.gov/pubmed/24877874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2014.05.008 |
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