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Synthesis and Biological Evaluation of QRSTUVWXYZA′ Domains of Maitotoxin
[Image: see text] The synthesis of QRSTUVWXYZA′ domains 7, 8, and 9 of the highly potent marine neurotoxin maitotoxin (1), the largest secondary metabolite isolated to date, is described. The devised synthetic strategy entailed a cascade Takai–Utimoto ester olefination/ring closing metathesis to con...
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| Publicado en: | J Am Chem Soc |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244842/ https://ncbi.nlm.nih.gov/pubmed/25374117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja509829e |
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