cAMP-responsive Element-binding Protein (CREB) and cAMP Co-regulate Activator Protein 1 (AP1)-dependent Regeneration-associated Gene Expression and Neurite Growth

To regenerate damaged axons, neurons must express a cassette of regeneration-associated genes (RAGs) that increases intrinsic growth capacity and confers resistance to extrinsic inhibitory cues. Here we show that dibutyrl-cAMP or forskolin combined with constitutive-active CREB are superior to eithe...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Ma, Thong C., Barco, Angel, Ratan, Rajiv R., Willis, Dianna E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239638/
https://ncbi.nlm.nih.gov/pubmed/25296755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582460
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