How Periplasmic Thioredoxin TlpA Reduces Bacterial Copper Chaperone ScoI and Cytochrome Oxidase Subunit II (CoxB) Prior to Metallation

Two critical cysteine residues in the copper-A site (Cu(A)) on subunit II (CoxB) of bacterial cytochrome c oxidase lie on the periplasmic side of the cytoplasmic membrane. As the periplasm is an oxidizing environment as compared with the reducing cytoplasm, the prediction was that a disulfide bond f...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Abicht, Helge K., Schärer, Martin A., Quade, Nick, Ledermann, Raphael, Mohorko, Elisabeth, Capitani, Guido, Hennecke, Hauke, Glockshuber, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239598/
https://ncbi.nlm.nih.gov/pubmed/25274631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.607127
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