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HMM-ModE: implementation, benchmarking and validation with HMMER3
BACKGROUND: HMM-ModE is a computational method that generates family specific profile HMMs using negative training sequences. The method optimizes the discrimination threshold using 10 fold cross validation and modifies the emission probabilities of profiles to reduce common fold based signals share...
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| Publicado no: | BMC Res Notes |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236727/ https://ncbi.nlm.nih.gov/pubmed/25073805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-483 |
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