A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment

BACKGROUND: To date, no therapeutic option has been established for sudden deafness refractory to systemic corticosteroids. This study aimed to examine the efficacy and safety of topical insulin-like growth factor-1 (IGF-1) therapy in comparison to intratympanic corticosteroid therapy. METHODS: We r...

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Published in:BMC Med
Main Authors: Nakagawa, Takayuki, Kumakawa, Kozo, Usami, Shin-ichi, Hato, Naohito, Tabuchi, Keiji, Takahashi, Mariko, Fujiwara, Keizo, Sasaki, Akira, Komune, Shizuo, Sakamoto, Tatsunori, Hiraumi, Harukazu, Yamamoto, Norio, Tanaka, Shiro, Tada, Harue, Yamamoto, Michio, Yonezawa, Atsushi, Ito-Ihara, Toshiko, Ikeda, Takafumi, Shimizu, Akira, Tabata, Yasuhiko, Ito, Juichi
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236431/
https://ncbi.nlm.nih.gov/pubmed/25406953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-014-0219-x
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