Carregando...
Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics
Tumor development is dependent upon the inactivation of two key tumor-suppressor networks, p16(Ink4a)–cycD/cdk4–pRB–E2F and p19(Arf)–mdm2–p53, that regulate cellular proliferation and the tumor surveillance response. These networks are known to intersect with one another, but the mechanisms are poor...
Na minha lista:
| Principais autores: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC423192/ https://ncbi.nlm.nih.gov/pubmed/15175242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1196704 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|