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Drug-target and disease networks: polypharmacology in the post-genomic era

With the growing understanding of complex diseases, the focus of drug discovery has shifted away from the well-accepted “one target, one drug” model, to a new “multi-target, multi-drug” model, aimed at systemically modulating multiple targets. Identification of the interaction between drugs and targ...

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Detalhes bibliográficos
Publicado no:In Silico Pharmacol
Main Authors: Masoudi-Nejad, Ali, Mousavian, Zaynab, Bozorgmehr, Joseph H
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230718/
https://ncbi.nlm.nih.gov/pubmed/25505661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-9616-1-17
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