The Circadian Clock Maintains Cardiac Function by Regulating Mitochondrial Metabolism in Mice

Cardiac function is highly dependent on oxidative energy, which is produced by mitochondrial respiration. Defects in mitochondrial function are associated with both structural and functional abnormalities in the heart. Here, we show that heart-specific ablation of the circadian clock gene Bmal1 resu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kohsaka, Akira, Das, Partha, Hashimoto, Izumi, Nakao, Tomomi, Deguchi, Yoko, Gouraud, Sabine S., Waki, Hidefumi, Muragaki, Yasuteru, Maeda, Masanobu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229239/
https://ncbi.nlm.nih.gov/pubmed/25389966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112811
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