The Circadian Clock Maintains Cardiac Function by Regulating Mitochondrial Metabolism in Mice

Cardiac function is highly dependent on oxidative energy, which is produced by mitochondrial respiration. Defects in mitochondrial function are associated with both structural and functional abnormalities in the heart. Here, we show that heart-specific ablation of the circadian clock gene Bmal1 resu...

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Vydáno v:PLoS One
Hlavní autoři: Kohsaka, Akira, Das, Partha, Hashimoto, Izumi, Nakao, Tomomi, Deguchi, Yoko, Gouraud, Sabine S., Waki, Hidefumi, Muragaki, Yasuteru, Maeda, Masanobu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229239/
https://ncbi.nlm.nih.gov/pubmed/25389966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112811
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