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Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response
Toll-like receptor 4 (TLR4) plays an important role in the regulation of the innate and adaptive immune response. Both agonists and antagonists of TLR4 are of considerable interest as drug leads for various disease indications. We herein report the rational design of two myeloid differentiation fact...
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| Veröffentlicht in: | Tetrahedron |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4228380/ https://ncbi.nlm.nih.gov/pubmed/25400297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.07.026 |
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