Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response

Toll-like receptor 4 (TLR4) plays an important role in the regulation of the innate and adaptive immune response. Both agonists and antagonists of TLR4 are of considerable interest as drug leads for various disease indications. We herein report the rational design of two myeloid differentiation fact...

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Udgivet i:Tetrahedron
Main Authors: Gao, Meng, London, Nir, Cheng, Kui, Tamura, Ryo, Jin, Jialin, Schueler-Furman, Ora, Yin, Hang
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228380/
https://ncbi.nlm.nih.gov/pubmed/25400297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2014.07.026
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