SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria

Sodium glucose cotransporter 2 (SGLT2) inhibitors have been reported to lower the serum uric acid (SUA) level. To elucidate the mechanism responsible for this reduction, SUA and the urinary excretion rate of uric acid (UE(UA)) were analysed after the oral administration of luseogliflozin, a SGLT2 in...

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Bibliografiska uppgifter
I publikationen:Biopharm Drug Dispos
Huvudupphovsmän: Chino, Yukihiro, Samukawa, Yoshishige, Sakai, Soichi, Nakai, Yasuhiro, Yamaguchi, Jun-ichi, Nakanishi, Takeo, Tamai, Ikumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2014
Ämnen:
Original Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223977/
https://ncbi.nlm.nih.gov/pubmed/25044127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.1909
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