SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria

Sodium glucose cotransporter 2 (SGLT2) inhibitors have been reported to lower the serum uric acid (SUA) level. To elucidate the mechanism responsible for this reduction, SUA and the urinary excretion rate of uric acid (UE(UA)) were analysed after the oral administration of luseogliflozin, a SGLT2 in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biopharm Drug Dispos
Prif Awduron: Chino, Yukihiro, Samukawa, Yoshishige, Sakai, Soichi, Nakai, Yasuhiro, Yamaguchi, Jun-ichi, Nakanishi, Takeo, Tamai, Ikumi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2014
Pynciau:
Original Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223977/
https://ncbi.nlm.nih.gov/pubmed/25044127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.1909
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