The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response of Mouse Spermatogonial Stem Cells

Germ cells are thought to exhibit a unique DNA damage response that differs from that of somatic stem cells, and previous studies suggested that Trp53 is not involved in the survival of spermatogonial stem cells (SSCs) after irradiation. Here, we report a critical role for the Trp53-Trp53inp1-Tnfrsf...

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Publicado en:Stem Cell Reports
Main Authors: Ishii, Kei, Ishiai, Masamichi, Morimoto, Hiroko, Kanatsu-Shinohara, Mito, Niwa, Ohtsura, Takata, Minoru, Shinohara, Takashi
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223695/
https://ncbi.nlm.nih.gov/pubmed/25358794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.006
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