The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response of Mouse Spermatogonial Stem Cells

Germ cells are thought to exhibit a unique DNA damage response that differs from that of somatic stem cells, and previous studies suggested that Trp53 is not involved in the survival of spermatogonial stem cells (SSCs) after irradiation. Here, we report a critical role for the Trp53-Trp53inp1-Tnfrsf...

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Foilsithe in:Stem Cell Reports
Main Authors: Ishii, Kei, Ishiai, Masamichi, Morimoto, Hiroko, Kanatsu-Shinohara, Mito, Niwa, Ohtsura, Takata, Minoru, Shinohara, Takashi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223695/
https://ncbi.nlm.nih.gov/pubmed/25358794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.006
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