ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling

Sorting and degradation of receptors and associated signaling molecules maintain homeostasis of conserved signaling pathways during cell specification and tissue development. Yet, whether machineries that sort signaling proteins act preferentially on different receptors and ligands in different cont...

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Pubblicato in:Cell Rep
Autori principali: Handschuh, Karen, Feenstra, Jennifer, Koss, Matthew, Ferretti, Elisabetta, Risolino, Maurizio, Zewdu, Rediet, Sahai, Michelle A., Bénazet, Jean-Denis, Peng, Xiao P., Depew, Michael J., Quintana, Laura, Sharpe, James, Wang, Baolin, Alcorn, Heather, Rivi, Roberta, Butcher, Stephen, Manak, J Robert, Vaccari, Thomas, Weinstein, Harel, Anderson, Kathryn V., Lacy, Elizabeth, Selleri, Licia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223648/
https://ncbi.nlm.nih.gov/pubmed/25373905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.019
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