Potential use of human adipose mesenchymal stromal cells for intervertebral disc regeneration: a preliminary study on biglycan-deficient murine model of chronic disc degeneration

INTRODUCTION: Biglycan is an important proteoglycan of the extracellular matrix of intervertebral disc (IVD), and its decrease with aging has been correlated with IVD degeneration. Biglycan deficient (Bgn(−/0)) mice lack this protein and undergo spontaneous IVD degeneration with aging, thus represen...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Marfia, Giovanni, Campanella, Rolando, Navone, Stefania Elena, Zucca, Ileana, Scotti, Alessandro, Figini, Matteo, Di Vito, Clara, Alessandri, Giulio, Riboni, Laura, Parati, Eugenio
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223513/
https://ncbi.nlm.nih.gov/pubmed/25293819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0457-5
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