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Ras Regulates SCF(β-TrCP) Protein Activity and Specificity via Its Effector Protein NORE1A

Ras is the most frequently activated oncogene found in human cancer, but its mechanisms of action remain only partially understood. Ras activates multiple signaling pathways to promote transformation. However, Ras can also exhibit a potent ability to induce growth arrest and death. NORE1A (RASSF5) i...

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Vydáno v:J Biol Chem
Hlavní autoři: Schmidt, M. Lee, Donninger, Howard, Clark, Geoffrey J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223314/
https://ncbi.nlm.nih.gov/pubmed/25217643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.594283
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