Targeting melanocyte and melanoma stem cells by 8-hydroxy-2-dipropylaminotetralin

Monobenzyl ether of hydroquinone (MBEH) is cytotoxic towards melanocytes. Its treatment efficacy is limited by an inability to eradicate stem cells. By contrast, 8-hydroxy-N,N-dipropyl-2-aminotetralin (8-DPAT) affects melanocyte stem cell survival. MBEH and 8-DPAT were added to melanocytes and melan...

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Bibliographische Detailangaben
Veröffentlicht in:Arch Biochem Biophys
Hauptverfasser: Bonchak, Jonathan G., Eby, Jonathan M., Willenborg, Kristin A., Chrobak, David, Henning, Steven W., Krzywiec, Anna, Johnson, Steven L., Le Poole, I. Caroline
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221435/
https://ncbi.nlm.nih.gov/pubmed/25132642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.07.033
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